If your wall has exposed wood or steel studs and is structurally adequate it is possible to mount the panels directly. It is important to remember that the bolts used to attach the climbing holds will protrude beyond the back of the panel. It is important to allow for adequate space for the bolts.
We do not recommend mounting panels directly to concrete and concrete block walls or walls that have been sheeted. When in doubt build a frame for your panels to mount to. A frame adds minimal cost and will increase the versatility and maintainability of your wall in addition to allowing you incorporate shapes and angle changes into your design.